Azumanga Daioh! The Druglord Game 2004

In this game you play the role of one of the biggest mob bosses in your country. However, all of your underlings have ran off to lead honest lives. To make matters worse, the meeting with your mob boss peers is fast approaching. An eccentric high school teacher named Yukari is willing to lend out three of her students as apprentice drug lords. It is your job to train them and choose the student most worthy of becoming your new drug lord.